A Maintenance Plan Matters Nutrition, physical activity, follow-up care, behavioral support, and sometimes continued medication or a procedure may be needed to maintain progress
Safety and efficacy of liraglutide, 3.0 mg, once daily vs placebo in patients with poor weight loss following metabolic surgery: the BARI-OPTIMISE randomized clinical trial
In practice, clinics adapt trial titration schedules by starting most patients at 1 mg once weekly for 24 weeks, which is considered the safest entry point for minimizing GI side effects
[1] The colour of faeces is primarily determined by bile pigmentsspecifically bilirubin and its metaboliteswhich undergo chemical transformation as they pass through the intestinal tract
Additionally, cardiovascular and metabolic benefits observed at therapeutic doses might be partially retained at lower doses, though this remains speculative without dedicated dose-finding studies