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Safety, Eligibility, and Provider-Guided Decision-Making Adverse event data in humans is sparse

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Excretion Pathways Radiolabeled studies in humans established PT-141s elimination pathways: 64.8% of administered dose recovered in urine 22.8% of dose recovered in feces Complete elimination occurring within several days No evidence of accumulation with repeated administration The predominantly renal excretion pattern and absence of accumulation support the approved dosing regimen of no more than one dose per 24 hours and maximum eight doses per month

doi: 10.1039/d1fo03675k 62 Van KaerLOlivares-VillagomezD