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4.2 Systemic inflammatory response syndrome and sepsis Since the onset of the coronavirus disease 2019 (COVID-19) pandemic, SIRS has gained attention because of its association with cytokine storm management efforts aimed at reducing morbidity and mortality (72)

Upon reduction of the disulfide, the shielding peptide can be displaced by wildtype SpyTag-equivalent peptide and the reaction can occur

Those four principles protect every peptide, regardless of how new or specialized it is

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