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As a triple receptor agonist (GIPGLP-1GCG) , Retatrutide targets multiple pathways involved in hunger and metabolism: GIP (Gastric Inhibitory Polypeptide) An incretin hormone released after eating that stimulates pancreatic beta cells to secrete insulin

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Recent research has linked endothelial dysfunction to dysregulation of non-coding RNAs (miRNAs, lncRNA) and alterations in gene regulatory networks (82)