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& Zernecke, A

ROS is generated in many cellular processes, such as protein synthesis, mitochondrial metabolism, cellular respiration, metabolism of organic matter through a redox reaction, and tissue homeostasis (Mailloux et al., 2013

For instance, analysis of the carnitine profile in plasma or serum is currently recognized as a diagnostic and monitoring method for detecting fatty acid oxidation defects and treating organic acidemia (Han et al., 2018)

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This work was supported by NIH grant R01DK031036 (to CRK) and Joslin Diabetes Research Center (DRC) grant (P30DK036836)