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Description

Level of action: Matrixyl can improve wrinkles from the root by promoting the production of collagen in the dermis, rather than just temporarily relieving them by filling or paralyzing muscles

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When released to the circulation, the bone-derived FGF23 binds to its receptor in epithelial cells of the proximal tubules of the kidney leading to decreased expression the type II sodium-phosphate co-transporters, NPT2a (encoded by the SLC34A1 gene) and NPT2c (encoded by the SLC34A3 gene)

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doi:10.1016/j.jaad.2015.08.038

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