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These stories highlight the profound impact that GLP-1 therapies can have on the lives of individuals with PCOS

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In vivo, circulating acetyl-L-carnitine concentration was increased 43% after oral acetyl-L-carnitine supplements of 2 g/day, indicating that acetyl-L-carnitine is absorbed at least partially without hydrolysis

They are likely related to complex downstream metabolic dysregulation induced by the disruption of incretin signaling rather than a proobesity effect of GLP-1 per se (94)