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Astrocytes have been shown to regulate BBB integrity through various mechanisms, such as mitochondrial transfer [44] and adhesion to laminins via the alpha7 integrin subunit [45]
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ROS directly damage membrane lipids, triggering lipid peroxidation, while the ERR-GLS1 axis regulates the ability of GPX4 to clear lipid peroxides by modulating the GSH/GSSG ratio (97)
Acquired megacolon occurs due to weakness and collapse of chronically stretched walls of the colon (Vieira 1996
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