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In the suit, Novo added that no head-to-head trials have compared the highest doses of Wegovy and Zepbound currently available on the market, so Lilly has "no basis to make these comparative claims" that its drugs are more effective

Physical examination revealed bilateral pitting pedal edema (2+), bilateral lung crepitations in the infrascapular region, and underdeveloped gonads (Tanner stage I)

This difference can probably be attributed to the fact that the reaction is very slow, and that after 15 days not all of the sulfur dioxide had been consumed

169,174 Moreover, delayed absorption of the concomitant drug due to delayed gastric emptying can be minimized by administering the drug 1 h before GLP-1 RAs or a dual GLP-1/GIP RA administration

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