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Sudhakaran G, Babu SR, Mahendra H, Arockiaraj J

Deveci et al showed that GSH enhances collagen contraction in human dermal fibroblasts and protects the keratinocytes from apoptosis under hyperglycemic conditions

Nevertheless, the kinetic data for our mutants and rate constants for ScGrx7 and PfGrx between 10 5 10 6 M 1 s 1 are too slow for a diffusion-controlled reaction and point towards important short-lived enzymesubstrate interactions and rate-limiting re-orientations of the substrate at the enzyme surface