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Secondary bile acids, modified by microbial bile salt hydrolases (BSH), function as signaling molecules through receptors such as FXR and TGR5, influencing microbial composition by selectively suppressing pathogens and promoting symbionts like Bacteroides 40,46

In the context of functional aging, L-leucine's role is not limited to muscle activity alone

Every minute outside the refrigerator counts toward that total, whether it is five minutes for an injection or five hours because you left it on the counter

In subjects with altered glucose tolerance, two LF gene polymorphisms (LF rs1126477 and rs1126478) were associated with HDL-C and TG levels ( Exogenous supplementation of LF could also improve energy metabolism (26, 27)

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