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Somatostatin feedback remains intact the pituitary responds to rising GH by reducing sensitivity, preventing runaway stimulation

Louie, L.J

This is a qualitative, mechanistic distinction between the two intervention categories, and it is why the research literature treats endpoint agonism and upstream secretagogue stimulation as fundamentally different manipulations of the somatotropic axis rather than two routes to the same outcome

The understanding of OSA and its implications on disease pathophysiology has undergone rapid evolution in recent years

Autoantibodies against alpha B-crystallin, a candidate autoantigen in multiple sclerosis, are part of a normal human immune repertoire