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The safety profile appears favorable for extended use based on available data, though long-term studies specifically on oral formulations do not exist

Collect the blood by cardiac puncture into a syringe containing a volume of Solution C equal to that of the expected blood volume (see Section 2c, Note 3)

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2 ACQUIRED MELANOCYTIC NEVI Acquired melanocytic nevi begin to appear after the first 6 months of life and increase in number during childhood and adolescence, typically reaching a peak count during the third decade and then slowly regressing with age

Blesa J, Foffani G, Dehay B, Bezard E, Obeso JA