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The Journal of Steroid Biochemistry and Molecular Biology
However, intravenous delivery does not allow for cell homing and in situ differentiation into tissue-specific functional cells because engraftment is often uncontrollable and mostly depends on chemotaxis toward a bioactive gradient
8 Data from a phase 2 trial of 338 adults with obesity without diabetes suggests substantial weight loss benefit with retatrutide, with 26% of participants having a body weight reduction of 30% with the highest dose of retatrutide (12 mg SC once weekly)
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