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Although there is no hard-and-fast way to determine how many drinks will bring you to the legal limit, there are ways to approximate your limit based on things like weight, how much youve had to drink, biological sex, and how long youve been drinking

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The consequent block of autophagy triggers the further accumulation of cellular waste like damaged mitochondria and protein aggregates, which contributes to overall cellular damage and leads to neuronal cell death and neurodegeneration 53