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Its substrate site-targeting mechanism inhibiting NNMT at the nicotinamide binding site provides selectivity over related methyltransferases and other enzymes in the NAD salvage pathway, making it a precise tool compound for studying NNMT-specific enzymatic activity in controlled laboratory systems
doi: 10.1152/japplphysiol.00371.2004 55
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Study of MDA-LDL by pioglitazone and pitavastatin in patients with type 2 diabetes
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