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The authors also wrote that their analysis of progression to wet AMD may have been underpowered due to the substantially smaller cohort size

The level of evidence of their efficacy is low, and none of them has a data sheet stating that it has been approved for use in PHH

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Once it goes off patent, orforglipron will be easy to produce and relatively cheap, which is what we want for this class of drugs, he said

Prospective trials incorporating longitudinal monitoring of neurological parameters and biomarker profiling are critically needed to validate these pharmacovigilance signals while elucidating doseresponse relationships and underlying mechanisms