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Lydia Alexander, president-elect of the Obesity Medicine Association and chief medical officer for Enara Health

The FDA prescribing information for both Mounjaro and Zepbound does not list osteoporosis, bone loss, or fractures as known risks of the medication

The honest framing has three parts: This is mechanistic reasoning, not a demonstrated effect

"I came out outspoken, so people mistook me as a blonde girl with no brain or talent because I was enabled at a young age by the father of my child," she says

For a sharper number, the Wegovy label, covering the same active ingredient at weight-management dosages, reports fatigue in 11% of treated adults versus 5% on placebo in the pooled weight-reduction trials