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The populations also differed: TRIUMPH-4 enrolled adults living with obesity and knee osteoarthritis over 68 weeks, while TRANSCEND-T2D-1 enrolled people living with type 2 diabetes over 40 weeks

PMID: 37366315

Furthermore, the NTS located GLP-1 neurons extend their dendrites into the circumventricular area postrema, an area with fenestrated capillaries that can sample blood borne factors (Llewellyn-Smith et al., 2011)

( Further reading: Where to buy retatrutide in the UK) In the TRIUMPH-1 Phase 3 trial, the most common retatrutide side effects were nausea, diarrhoea, constipation and vomiting

Stop using this medicine at least 2 months before you plan to get pregnant