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For patients with severe symptoms, treatment starts with 1000 mcg injected intramuscularly once daily for 7 days, then the frequency can vary to 1-3 times weekly for 4-8 weeks

AOD-9604 was developed to: Stimulate lipolysis (breakdown of stored fat) Inhibit lipogenesis (formation of new fat) Avoid raising IGF-1 levels Reduce impact on blood glucose Because it is a small fragment rather than the full hormone, it theoretically targets fat metabolism more specifically

For months, I couldnt get a full night of rest

For an 8mg dose: 8mg / 5mg per mL = 1.6mL

Managing combined side effects Expect amplified GI effects: Both peptides slow gastric emptying Synergistic nausea (not just additive) Constipation very common Weeks 9-16 most challenging Nausea management protocol: Prevention from day 1 (ginger, small meals) Prescription anti-nausea (Zofran) essential Liquid nutrition if needed Slower titration if poorly tolerated Constipation prevention: 80-100 oz water daily Fiber 25-30g daily Magnesium citrate 300-500mg nightly MiraLAX as needed Nutrition maintenance: Protein shakes 2-3 daily (30-40g each) Target 60-80g protein minimum Multivitamin daily B12 supplementation When to reduce doses: Severe persistent nausea despite management Unable to maintain adequate nutrition Vomiting frequently Quality of life severely impacted See our common peptide mistakes beginners make to avoid errors