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Specification and emulation of the studies To inform our study design and analytic approach for the head-to-head tirzepatide versus semaglutide comparison of interest, we sought to conduct studies that allowed us to benchmark results of similarly designed database studies against results from randomized trials asking closely related questions

PROTOCOL FOR SUCCESS PRESCRIBING TIPS: Start low, go slow: Initiate at 0.25 mg weekly x 4 weeks to improve GI tolerance

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