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[3] [17] The American Diabetes Association's Standards of Care emphasizes the importance of patient education regarding these potential adverse effects and appropriate monitoring during treatment initiation and dose titration

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Neurons of the CNS are very active in oxidative metabolism, as they are constantly exposed to lowtomoderate levels of ROS, and these species are removed by antioxidants (melatonin, vitamin D, vitamin E, glutathione) and antioxidant enzymes (superoxide dismutase, catalase, glutathione peroxidase, etc.)

Prog Neuropsychopharmacol Biol Psychiatry 30, 15291531 (2006)

That means testosterone production can stay more consistent and efficient, especially under pressure from stress or environmental toxins