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When mitochondria are depolarized, the loss of mitochondrial membrane potential stabilizes PINK1 on the outer mitochondrial membrane (OMM), where it recruits and phosphorylates Parkin at serine 65 within its ubiquitin-like (UBL) domain, amplifying Parkins recruitment to the OMM [25]

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In the hair follicle, certain stem cells act as reservoirs of pigment-producing cells