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GLP-1s are known for disrupting treatment paradigms, but they also expose the cracks in patient access and adherence

But that has not been established in humans, and there are very limited ongoing clinical trials to illuminate the real efficacy and safety of these peptides

Eligibility for peptide therapy varies from person to person

The side effect profile is more serious than GLP1R agonists , including depression and suicidal ideation and it is not approved for other types of obesity

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