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In a randomized, placebo-controlled trial in 1,374 participants who had colonoscopic removal of at least one colorectal adenoma (the Selenium and Celecoxib trial), selenium supplementation (200 g/day with selenized yeast) for a median of 33 months had no effect on colorectal adenoma recurrence (88)

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Clinical trials show approximately 15-22% weight reduction over 68 weeks with semaglutide in weight-management studies

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