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Some patients confuse their dose in milligrams with units and attempt to draw 5 units for a 5mg dose

Furthermore, although some experiments indicate possible interactions with DNA, the absence of significant cytotoxic effects diminishes the biological relevance of these findings and their potential therapeutic applicability

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Moreover, the antibody notably inhibited the expression of proinflammatory mediators and alleviated the overactivation of glial cells, thereby effectively disrupting the HMGB1initiated inflammatory cascade in the acute phase of injury [349, 350]