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Treated APP/PS1 mice showed significant improvements in spatial learning and memory compared to untreated transgenic controls, with molecular analysis confirming activation of PI3K/AKT signaling in hippocampal tissue

GLP-1 receptor agonists like semaglutide and liraglutide intentionally slow gastric emptying as part of their therapeutic mechanism, but distinguishing this expected effect from true gastroparesis presents diagnostic challenges

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