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(2005) In vitro percutaneous absorption of pine bark extract (Pycnogenol) in human skin

All statistical analyses were performed using Graph Pad Prism 9.3 software

The resulting metabolic dysregulation includes impaired thermogenesis, altered glucose and lipid metabolism, and a tendency toward insulin resistancefactors that also contribute to MetS and increased CVD risk [40,41]

Compared to individual GLP- 1 receptor agonists, its action on GIP and GLP- 1 receptors improves appetite control and metabolic function, indicating higher efficacy [117]