106 Following pioneering studies that linked CBS overexpression with colorectal and ovarian cancer (Table 1), an increase in the expression of all enzymes involvedindividually or jointlyin the synthesis of H 2 S has also been reported for breast, gastric, lung, liver, bladder, kidney and prostate carcinomas, melanoma, neuroblastoma, glioma and astrocytoma
For histological and molecular analyses, data were derived from multiple tissue sections per sample to account for intra-sample variability
Notably, the G/D-CuP group showed the lowest ratio of CD86-positive macrophages/CD206-positive macrophages, indicating an enhanced M1-to-M2 transition (Supplementary Fig
2018;87:1411 doi: 10.1016/bs.acc.2018.07.004
[DOI] [PubMed] [Google Scholar] 261.Krivic A., Anic T., Seiwerth S., Huljev D., Sikiric P