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It is a specific 16-amino acid fragment of human growth hormone, corresponding to the region between amino acids 176 and 191

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While B12 is generally safe, caution is needed in specific clinical situations: Lebers Disease (Hereditary Optic Neuropathy): B12 injections are generally contraindicated or should be used with extreme caution, as they may potentially aggravate optic atrophy in this rare condition

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