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Examination of this hypothesis revealed the presence of CzNIS1a, CzNIS1b and CzEcp2, all of which are homologous to effectors known to activate immunity in non-host species as a result of their activity (Stergiopoulos et al., 2010

genetic associations with other risk factors were obtained from summary statistics in the Neale Lab GWAS of the UK Biobank, controlling for age, age 2 , and 20 principal components (Additional file 1: Table S1)

doi: 10.1016/j.freeradbiomed.2008.10.040 114 HatiS.BhattacharyyaS

28 The association between sleep apnea and blood pressure is likely bidirectional and driven by a number of factors, including overactivation of the sympathetic nervous system, oxidative stress resulting from intermittent hypoxia (periods of low oxygen levels), and disruption of hormone levels

From both the mechanistic and clinical standpoints, it is reasonable to expect that GLP-1s and SGLT2s would produce additive CV and renal protective effects