This cell line was selected after a study reporting that mycophenolic acid, an IMPDH2 selective inhibitor, was more effective at inhibiting cancer cell proliferation in fast-growing cell lines, such as HeLa and Caco2, than in slow-growing cells 48 , suggesting that HeLa cell viability would be sensitive to IMPDH2 degradation
Further, tirzepatide activates the GLP-1 and GIP receptors in the brain and white adipose tissue, resulting in reduced appetite, improved insulin sensitivity, and weight loss
enm-2024-2164-Supplemental-Fig-S3.pdf Article information CONFLICTS OF INTEREST No potential conflict of interest relevant to this article was reported
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