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Contraindications and special populations : Berberine should be avoided during pregnancy and breastfeeding due to insufficient safety data

However, a more localized synaptic expression of MET in the adult brain was indeed shown (Tyndall and Walikonis, 2006, 2007)

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a pretreatment with methadone but not with morphine produced a cross-desensitization with [D-Ala 2 , D-Leu 5 ]-enkephalin (DADLE) and morphine (Liu et al., 1999a)

However, during ovarian aging, defects in PINK1/Parkin-mediated mitophagy further promote ferroptosis and apoptosis (Khan et al., 2023