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Fibroblasts were incubated with d3-palmitate and L-carnitine in duplicate for 72 h to determine function of the fatty-acid oxidation pathway (Baylor Institute of Metabolic Disease, Dallas, TX)

doi:10.1037/pst0000125

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Figure 1 The hallmarks of cancer, proposed by Hanahan and Weinberg ( Metabolic inhibitors have been used for cancer therapies for many years, including the anti-metabolite class of chemotherapy ( Herein, we will discuss how metabolism is reprogrammed in prostate cancer, in both localized and mCRPC, which likely have different metabolic needs