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Furthermore, acute exposure of isolated mouse islets or INS-1(832/13) -cells to the oxidative stressors, arsenite, 4-hydroxynonenal, or methylglyoxal, decreased insulin secretion ( Circulating metabolites, like -hydroxybutyrate that enter cells and increase NADH and ROS production in -cells, increase insulin secretion (Figure 6A)

Possible side effects associated with long-term use (12-24 months) have yet to be established in clinical research studies

Manufactured under strict GMP-certified standards, it ensures safety, potency, and consistent therapeutic performance, making it suitable for hospital and clinical use

Reduces risk of cardiovascular complications in patients with diabetes (under ongoing study)