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If youre losing weight very rapidly, more frequent scans could help catch muscle loss early

Some analyses estimate that 1540% of weight lost on GLP-1 drugs may come from lean mass 5 , including muscle, rather than fat

In a Staphylococcus aureus -induced mastitis model, intake of high-dose inulin was shown to inhibit HDAC3 by promoting butyrate production in mice, thereby activating the macrophage-mediated antimicrobial defense program ( - monocytes, and enhanced alternative macrophage activation, thereby inhibiting CXCL1 production, neutrophil recruitment, and the immune response during infection (108)

In principle, there could be weak or strong evidence, either in favor of or against, the hypothesis that incretin-based medications can increase the risk for pancreatic, (medullary) thyroid, or other carcinomas

A Phase 2 clinical trial published in the New England Journal of Medicine in 2023 reported mean body weight reductions of approximately 24% at 48 weeks at the highest studied dose