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In infants, pyridoxine deficiency can cause irritability, abnormallyacute hearing, and seizures, which are unresponsive to anticonvulsants but respond to pyridoxine supplementation ( A study performed by Yang and Wang in 2009 showed in-vivo study that pyridoxine can inhibit glutamate release from cerebrocortical synaptosomes by suppressing voltage-dependent Ca2+ entry

Those two compounds alone have never been shown to have any benefit to justify them being used therapeutically in humans, says Taylor

However, the overall impact on health is relatively minor

It forms a non-occlusive film on the skin's surface to provide a silky feel without being greasy