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although in some cases, the macules may be confused for melanoma in situ (a precancerous skin condition) In a majority, no treatment of Vulvar Melanotic Macules may be necessary and the healthcare provider may undertake a wait and watch approach

Umano GR, Pistone C, Tondina E, Moiraghi A, Lauretta D, Miraglia del Giudice E and, Brambilla I

50,51 As expected, cinchonine dose-dependently reduced body weight gain in ob/ob-GAN NASH mice, which was consistent with decreased food intake