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Gradually increase to 550 mg twice daily, and let your doctor adjust your semaglutide dose as needed

In the Phase 3 trial, Lilly tested the two strongest doses of retatrutide, which works on three different hormones that affect appetite and metabolism, in adults who were overweight or had obesity and also had knee osteoarthritis, but did not have diabetes

This highlights the variability in patient responses and the need for individualized treatment plans