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Third, information on changes in body weight was unavailable in the NHIRD, we were unable to evaluate risks of anxiety or depression related to body weight changes

They generally interact with key glands: the hypothalamus, pituitary, thyroid, adrenals, ovaries, and testes either through direct binding or through influencing upstream signals

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PCa resistance mechanisms include low tumor mutational burden and lack of PD-1 expression, which are often observed in patients (47,48)