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Combined autophagy and HDAC inhibition: a phase I safety, tolerability, pharmacokinetic, and pharmacodynamic analysis of hydroxychloroquine in combination with the HDAC inhibitor vorinostat in patients with advanced solid tumors

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Using a novel, rabbit-derived polyclonal antibody specific for IGF-1Eb, we demonstrate for the first time the specific patterns of neuronal expression of MGF in mouse brain and that MGF plays a role in preventing neuronal attrition and brain dysfunction in aging mice