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Adicionalmente, mantener la funcin mitocondrial durante perodos de restriccin calrica es importante, ya que dficits calricos prolongados pueden asociarse con reducciones en el contenido y funcin mitocondrial que comprometen la capacidad de oxidar sustratos energticos eficientemente

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These findings suggest a substantial degree of central sensitization in cirrhosis, highlighting nociplastic pain as a crucial component of chronic pain in these patients (68, 81)

In a meta-analysis examining the efficacy of metformin treatment for GDM, it was found that the incidence of severe neonatal hypoglycemia was significantly reduced in the metformin-treated GDM group, potentially due to improved maternal glycemic management (Nilsen et al., 2024

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