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Zhongguo Zhong Xi Yi Jie He Za Zhi (2011) 31:126972
In one study, FI-SARS-CoV reduced viraemia and protected against lung pathology in rhesus macaques 124 , whereas in another study macaques given FI-SARS-CoV developed macrophage and lymphocytic infiltrates and alveolar oedema with fibrin deposition after challenge, indicating the difficulties of establishing consistent NHP models 125
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