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Moreover, excessive intracellular levels of ROS may damage lipids, proteins and DNA, and this ability has been exploited in a series of anticancer strategies, as detailed below
The oligo annealing and subcloning into the Cas9 nuclease reporter vector were performed according to the manufacturers instructions
It helps to reduce the effects of oxidative stress, which is a major contributor to aging
Mol Cell Endocrinol 93 : 193198 Resnicoff M, Sell C, Rubini M, Coppola D, Ambrose D, Baserga R, Rubin R (1994) Rat glioblastoma cells expressing an antisense RNA to the insulin-like growth factor-1 (IGF-1) receptor are nontumorigenic and induce regression of wild-type tumors
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