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Mechanism of Action IGF-1 DES exerts its anabolic and metabolic effects through high-affinity binding to and activation of the IGF-1 receptor (IGF1R), a receptor tyrosine kinase that is widely expressed across virtually all cell types in the body and serves as the primary mediator of IGF-1's growth-promoting, anti-apoptotic, and metabolic actions

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Other animal studies have also shown that asparagus may help regulate lipid metabolism, lower cholesterol levels, reduce blood pressure, and promote weight loss in mice

10.18632/oncotarget.7598 61 HassanniaB.VandenabeeleP.BergheT

Adrenergic signaling in muscularis macrophages limits infection-induced neuronal loss