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Moreover, the C-terminal serine of the peptide was replaced by cysteine via site-directed mutagenesis performed with polyethylene glycol

Multiple sclerosis treatment includes disease-modifying therapies such as interferon beta, glatiramer acetate, and newer oral agents (fingolimod, dimethyl fumarate) or monoclonal antibodies (natalizumab, ocrelizumab)

The emergence of biosimilars and cost-effective manufacturing methods may reduce financial obstacles, but need regulatory frameworks that promote competitive markets while upholding quality standards

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