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Thus increased oxidative stress, loss of Na + /K + -ATPase activity, and altered biochemical markers of mitochondrial function play a role in the increased excitotoxicity in individuals with hyperprolinemia

Omics technologies provide more comprehensive molecular profiling, and can be employed to screen NP toxicity at low exposure levels, and also have the advantage of identifying new biomarkers and targets of nanotoxicity both in vivo and in vitro

Keep simple logs of injection timing, sites, doses, and any effects noticed

J Intern Med 272:9397 Schmid C, Neidert MC, Tschopp O, Sze L, Bernays RL (2013) Growth hormone and klotho

Real-world vignette: separating effect from context Consider a patient who feels tired and has been snacking mindlessly