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Watson Bakeerathan Gunaratnam Yana Feygin Stephen P
Three glutathione adducts of the drug melphalan, used to treat ovarian cancer and multiple myeloma, have been isolated from reactions involving human microsomal GSTs Target
Ruscogenin attenuates cartilage destruction in osteoarthritis through suppressing chondrocyte ferroptosis via nrf2/slc7a11/gpx4 signaling pathway
Lead Researcher Spotlight Professor Frank Ng, PhD Department of Biochemistry and Molecular Biology Monash University, Melbourne, Australia Professor Frank Ng led the pioneering research team that developed AOD-9604 in the 1990s as part of efforts to create a targeted anti-obesity therapeutic derived from human growth hormone
Collectively, these findings emphasize that IGF-1s role in PAH is highly context-dependent, being protective under certain conditions but potentially pathogenic under others
