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Binding at this receptor triggers intracellular calcium signaling cascades in somatotroph cells of the anterior pituitary, leading to growth hormone release in a pulsatile pattern that mimics physiological secretion in animal models

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This is a meaningful data set, and digging into the distribution tells a more nuanced story than the headline number

How the agency balances efficacy against that safety signal will determine the final indication and prescribing guidance

Delivery systems for administration of LH-RH agonists to patients with prostate cancer are efficacious, convenient and also promote patient compliance