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2.2 Major exposure pathways and representative cases Human EED exposure occurs through multiple routes, with patterns varying significantly based on occupational activities, environmental conditions, and consumer behaviors

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Notably, mutations in TP53 not only change its conformation but also cause p53 aggregation, and p53 aggregation in cells is more consequential than conformational changes

Surgery can relieve the immediate danger, but it often leaves lasting effects, such as chronic diarrhea or dietary restrictions, that change daily life

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